According to recent estimates South Africa has the highest number of HIV cases in the world with more than 6.5 million South Africans being infected. However, the South African health authorities have responded superbly building the largest ARV treatment programme in the world with approximately 3 million people on the publicly funded ART programme. Between 2003 and 2012 it is estimated that approximately 780 thousand lives have been saved through this programme.
Vx Pharma sees clinical research as a key contributor to the success of combating the disease as well as a large opportunity to grow our activity in the research community. The HIV offering by Vx Pharma is relatively new, having been launched in 2013, but already the company has successfully conducted two large inpatient studies in treatment naive patient cohorts for leading Big Pharma sponsors. Currently the focus for the HIV therapeutic area is on Phase1b-2a studies as well as bioequivalence in patients on standard of care (best practice for BE studies on ARVs). Vx Pharma has an unprecedented capability to recruit and manage HIV patients (both treatment naive as well as on ART) through its close relationship with a number of HIV clinics and ARV programme centres. The company is also in discussions with several potential partners to open large Phase 3 centres collocated at the largest HIV centres around the region.
Principle Investigator: Dr Zinhle Makatini
Vx Pharma is pleased to announce that it has entered into a formal exclusive working relationship with one of the Country’s foremost HIV clinicians and researchers. Dr Makatini serves on the Clinical Trials Committee of the Medicines Control Council (MCC) and is the principle reviewer of HIV research protocols for the Council. She served as a Member of the MCC until 2014 and is currently reading for her PhD degree.
Dr Makatini holds the following qualifications:
· FCPath (Virology) degree from WITS University, South Africa
· MBChB Degree from the University of Sheffield, UK
· MSc Degree (Immunology of Infectious diseases) from the University of London, School of Tropical Medicine and Hygeine, UK
· BSc (Hons) (Biochemistry) Degree from the University of London, Kings College, UK
· Several Diplomas in HIV Management, HIV Medicine and Travel Medicine